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In order to adjust for confounders, the following covariate variables were selected as the independent variable: age, race, ethnicity, sex, BMI, history of chronic kidney disease (CKD), history of congestive heart failure (CHF), history of diabetes, history of gastric surgery, history of gastroparesis, whether bowel prep was used (e.g., underwent same day EGD-flexible sigmoidoscopy or EGD-colonoscopy), history of GLP-1RA use, and other medications known to contribute to delayed gastric emptying
Additional information is provided as Clinical Principles and Expert Opinion when insufficient evidence existed
Originally developed for blood sugar control in patients with type 2 diabetes, it is now recognized for its significant ability to help reduce appetite, lower cravings, and support meaningful long-term weight reduction
This is particularly important if you have a history of gastrointestinal problems, cardiovascular disease, kidney impairment, or if you are pregnant or breastfeeding, as these conditions may influence the safety profile of either medication
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