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Therefore, further investigation is warranted through large-scale, extended-duration, monotherapy-focused Phase III trials to corroborate these findings and establish definitive efficacy and safety parameters (145)

Studies show that female rodents have higher mitochondrial GSH levels and antioxidant enzyme activities, linked to estrogen-mediated activation of MAPK and NF-B signaling pathways, suggesting sex-based differences in redox resilience (37-39)

The state is a great place to pass legislation, work with insurance companies, and work with the patient community to make sure they have access, she says