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More research is needed before GLP-1 drugs can be recommended for breast cancer prevention

Mechanisms of Nafld development and therapeutic strategies

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Disruption of this integrated network (e.g., via ferroptosis inhibitors targeting ACSL4/GPX4, anti-inflammatory agents blocking HMGB1/IL-33, or HIF modulators balancing hypoxia adaptation) can break the pathogenic cycle, highlighting the therapeutic potential of targeting the networks central nodes rather than individual pathways