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Two recent phase 3 multicenter randomized trials in adults with obesity showed that tirzepatide, a novel dual gastric inhibitory peptide\GLP-1R agonist, caused substantial weight loss in patients who failed to lose weight via dietary changes and noninferior and superior glycemic control compared to semaglutide in those with comorbid T2DM [118, 119]

Additionally, GPX4 is capable of reducing complex lipid compounds and it is the only enzyme in the GPX family that directly reduces and destroys lipid hydroperoxides

While there may not be anything specifically wrong with putting on a patch if you can afford it, they are not a panacea

This minor surgery results in high quality of life and is a durable long term solution