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Lassaunire R, Frische A, Harboe ZB, Nielsen AC, Fomsgaard A, Krogfelt KA et al (2020) Evaluation of nine commercial SARS-CoV-2 immunoassays

Using a high-gauge (thin) needle and inserting it at a slight angle can help minimize this risk, protecting the purity of your solution.

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This concept not only addresses the discussions in this paper regarding payload reconciliation and target heterogeneity but also signifies the potential for a shift from structural-level optimization to system-level design