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Description

Each item is scored on a scale from 1 (within normal limits) to 4 (severely abnormal), yielding a total score range of 1560

Timeline: Measurable biomarker shifts at 2-4 weeks

They have been extensively studied in large randomised controlled trials, with success rates of 60-70% across various causes of ED

Activated LRRK2 then increases intracellular iron content by enhancing Fe 2+ uptake, which in turn induces ROS generation and pro-apoptotic molecule expression