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10.1111/ijlh.13885 3

Non-canonical ubiquitination and SUMOylation in NDDs In addition to canonical K48-linked ubiquitination that targets proteins for proteasomal degradation, alternative ubiquitin chain architectures and ubiquitin-like modifications play critical roles in neuronal signaling and survival (Fig

Albumin data were obtained from the KORA study (Shin et al., 2014)

Increase their intake of antioxidants, such as glutathione, that are helpful for the reduction of oxidative stress that can occur as a result of general anesthesia