The homogenates were centrifuged at 20,400 g for 20 min at 4 C, and the resulting supernatants were appropriately diluted and used in the assays, which were conducted according to the manufacturers instructions
The intervention of Lentinan (LNT, 2.5 and 5 mg/kg) also significantly enhanced the activity of superoxide dismutase (SOD) and reduced the levels of malondialdehyde (MDA) in the hippocampus of mice with chronic unpredictable stress-induced depression (Ma et al., 2015)
During propagation, lipid radicals react with molecular oxygen to form lipid peroxyl radicals (LOO), which subsequently abstract hydrogen atoms from adjacent phospholipids, thereby generating new lipid radicals and lipid hydroperoxides (LOOH)
This activation: Promotes directed cell migration toward injury sites Enhances cellular outgrowth from damaged tissue edges Improves cell survival during the stressful healing process Facilitates proper tissue organization This mechanism is particularly relevant for tendon and ligament healing, where cellular organization and proper fiber alignment are critical for functional recovery
