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BPC 157 has beneficial effects on inflammation, hemorrhage, and edema after traumatic brain injury [33], various severe encephalopathies (which follow gastrointestinal and/or liver lesions), NSAID overdose [34,35,36,37], or insulin overdose seizures [38] and on severe muscle weakness after exposure to the specific neurotoxin cuprizone in a rat multiple sclerosis model [39] or magnesium overdose [40]

doi:10.1021/acs.jmedchem.9b00657 7

Pregnancy and breastfeeding are also contraindicated due to a lack of safety data for systemic use in these populations

doi: 10.1111/j.13652826.2004.01218.x 172 WongAOLLiWLeungCYHuoLZhouH