Although individual components have been shown to be safe [142], excessive consumption, especially among adolescents, often leads to potential adverse effects on human health
52 , 133 In an extensive multiinstitutional study including over 5 million obese adults, GLP1RA therapy (notably liraglutide, dulaglutide, and semaglutide) was associated with significantly lower risks of Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders, alongside reduced allcause mortality
Although these are well-established indicators of lipid peroxidation and antioxidant response, inclusion of additional markers such as intracellular ROS production, superoxide dismutase, glutathione peroxidase, and NO-related parameters may provide enhanced mechanistic insight
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