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Introduction Epidemiology and co-occurrence Proposed mechanisms linking IR and BD Clinical consequences of IR in bipolar disorder Mechanisms impacting brain and behavior Clinical implications and treatment perspectives References Further reading Insulin resistance is highly prevalent in bipolar disorder and is increasingly linked to worse clinical outcomes, treatment resistance, and neuroprogression

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To understand the relations between the diverse genetic factors contributing to T2D development and to improve current detection and prevention protocols, we set out and use machine learning approaches to analyze two T2D large-scale genetic datasets

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