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Can occur with both Vyvanse and Adderall: cardiovascular problems, such as fast heartbeat, increased blood pressure, or in rare cases, heart attack, stroke, or sudden cardiac death (heart suddenly stops beating) problems with blood circulation in your fingers and toes, such as Raynauds syndrome mental health conditions, such as psychosis or mania serotonin syndrome slowed growth in children allergic reaction potential for misuse and dependence* * Both Vyvanse and Adderall have a Effectiveness The only condition both Vyvanse and Adderall are used to treat is ADHD