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The SELECT cardiovascular outcomes trial showed that semaglutide 2.4 mg significantly reduced major adverse cardiovascular events (heart attack, stroke, and cardiovascular death) in patients with established cardiovascular disease and overweight or obesity, even without type 2 diabetes

Glucagon-like peptide 1 (GLP-1) agonists are a class of drugs that are approved by the FDA for weight loss in obese people without diabetes or to treat type 2 diabetes

The peptide promotes angiogenesis and osteoblast activity through VEGFR2-NO signaling

Although some healthcare providers may prescribe Zepbound off-label for fatty liver disease, it is still being researched and is not yet FDA approved for this use