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Molecular mechanisms of mitochondrial DNA release and activation of the cGAS-STING pathway

Grade I (mild sprain) Goals Control pain and swelling Restore knee range of motion (ROM) Begin muscle activation, particularly quads and hamstrings Gradually reintroduce load Typical plan Acute / protection phase (days 13 or until pain allows) Rest (avoid aggravating activities) Ice, compression, elevation Gentle passive / active assisted knee flexion/extension (within tolerance) Quadriceps sets (isometric contraction) Straight leg raises if pain allows Early rehab (week 12) Progress ROM (heel slides, wall slides) Light closed-chain loading (mini squats) Gentle hamstring activation Begin balance / proprioception (e.g

Produced by the liver, glutathione consists of three main amino acids, namely glycine, cysteine, and glutamine