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It contains semaglutide, a GLP-1 receptor agonist that may help regulate appetite and food intake through the braingut connection

[37] Its the same pattern we see with other lifelong conditions, such as high blood pressure or cholesterol

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This has been attributed in part to reduced expression of their receptors as a consequence of glucotoxicity [2], a possibility supported by the observation that normalisation of blood glucose levels in patients with type 2 diabetes restores the efficacy of GLP-1 and GIP [3]