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In the clinical treatment of DKD, SGLT2 inhibitors have demonstrated substantial renal protective effects across many large-scale clinical trials ( 3.1 System pharmacology of SGLT2 inhibitors The first SGLT2 inhibitors came from phlorizin, a natural plant compound

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Other evidence-based interventions include: Optimising management of associated conditions such as diabetes, hypertension, and dyslipidaemia Coffee consumption, which observational studies associate with reduced liver disease progression Avoiding hepatotoxic medications when possible Regular monitoring through your GP is essential

Using a skin pinch for lean areas and choosing the abdomen (which typically has the most subcutaneous fat) can help prevent this