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Methylene Blue What It Is: Methylene Blue is a compound originally used as a dye in medical diagnostics but has recently gained attention for its neuroprotective properties

This is most likely due to the discontinuation of the previous GLP-1 RA therapy and other oral glucose-lowering medications (DPP-4is, glinides and sulfonylureas) at randomisation, combined with the gradual up-titration of IcoSema or escalation of semaglutide from a lower initiating dose than participants were receiving before the trial

There is no solid evidence that GLP-1 meds cause NAION, and the absolute risk if there even is one is so low it barely registers