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Clarifying the core mechanisms and key influencing factors of the contradictory conclusions on the regulatory effects of mitophagy is not only of great significance for in-depth understanding of the role of mitophagy in the occurrence and development of related diseases, but also provides important theoretical support for subsequent disease prevention and treatment strategies targeting mitophagy

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Second, while we concurred that avoiding post-cystoscopy infections is important, we noted that none of the studies the applicant submitted as evidence evaluated or assessed the VersaVue [TM] Single-Use Flexible Cystoscope and that none of the studies compared clinical outcomes, such as adverse events (including post-cystoscopy infection) associated with the use of the VersaVue [TM] Single-Use Flexible Cystoscope to clinical outcomes associated with reusable cystoscopes

Your provider will determine whether additional testing is appropriate