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During dialysis, patients experience subnormal plasma/serum free carnitine concentrations [13] with plasma levels dropping by 60% with a slow replacement from carnitine stores such as from skeletal muscle during the interdialytic period
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We then capped any unreacted cysteine thiol and cysteine persulfide using -(4-hydroxyphenyl)ethyl iodoacetamide (HPE-IAM) and analyzed the intact mass product distribution using ESI-MS
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