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In addition, activation of GLP-1Rs has anti-inflammatory effects via stimulation of AMPK, cAMP, endothelial nitric oxide synthase (eNOS), and suppression of chemokine expression (Jin and Liu 2020)

While adult obesity rates have driven commercial focus, childhood obesity has reached epidemic proportions globally, with limited therapeutic options available for younger patients

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It is no wonder that more patients like Mr T are now taking the initiative to request these treatments