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No, the medications themselves do not directly damage your skin or cause Ozempic face. The sagging is simply a physical result of rapid fat loss

The arginine substitution at position 3 greatly reduces the peptides affinity for IGFBPs by about 100-fold compared to native IGF-1

Key reasons GLP-1s require heightened caution in eating disorder populations include: Appetite suppression that may reinforce restrictive behaviors Rapid or significant weight changes that can increase psychological distress Heightened focus on food intake, body cues, or weight-related outcomes Temporary behavioral changes that may mask symptoms rather than address underlying drivers Eating disorders are multifaceted mental health conditions that cannot be effectively treated through appetite or weight changes alone

1 Glutamine is utilized in a number of vital functions, including protein synthesis and production of the nucleotide units that make up DNA and RNA