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Where a compound (or combination) has not been studied for a use, the responsible default is to say so, rather than to fill the gap with mechanism talk and cross-species extrapolation

Many people use supplemental B12 to improve energy and physical performance

for instance, DT-109 (Gly-Gly-Leu) markedly reduced atherosclerosis and vascular calcification in nonhuman primates, underscoring the translational potential of tripeptide-based therapeutics for cardiovascular diseases [181]