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Contraindications Do Not Use If You Have active or suspected malignancy (cancer) sermorelin should not be used until the cancer is successfully treated Have had a serious hypersensitivity reaction to sermorelin or any component Have an acute critical illness following heart or abdominal surgery, multiple accidental trauma, or acute respiratory failure Are pregnant or breastfeeding Are a child with closed epiphyses (for non-pediatric indications) Warnings and Precautions Hypothyroidism: May develop or worsen during sermorelin therapy

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doi: 10.1074/jbc.R113.458810 15