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However, post-treatment care is important to maintain results and manage any lingering side effects

presented a model in 2010 for beta-cell neogenesis in which mature alpha-cells rapidly replicate and convert efficiently into beta cells following PDL and alloxan treatment

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Maintenance dosing considerations: Community protocols commonly describe two maintenance approaches after the initial 8-12 week loading phase: (1) reduced frequency at the same dose (e.g., IV once monthly instead of weekly), or (2) transitioning from injectable/IV to high-bioavailability oral (liposomal) for convenience while accepting a modest reduction in peak levels