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Description SLU-PP-332 Peptide SLU-PP-332 is a synthetic compound investigated for its activity as a REV-ERB/ agonist , Chemical Makeup Molecular Formula: C30H35N5O3 Molecular Weight: 513.63 g/mol Mechanism of Action: REV-ERB/ receptor agonist Solubility: DMSO, ethanol Structure Type: Non-peptidic small molecule Research Use Only SLU-PP-332 is provided for in vitro and in vivo laboratory research use only

Disclosure of interest: DL has received advisory board honoraria from Boehringer Ingelheim and a consultancy payment for this study from Bayer

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In animal cells the fate of ITCs is well characterized: conjugation to glutathione by GSTs resulting in its intracellular depletion and subsequent degradation of dithiocarbamates through enzymatic events catalysed by -glutamyltranspeptidase, cysteinylglycinase and N -acetyltransferase via the mercapturic acid pathway 76