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Nurse Erika St

The SURMOUNT-1 trial found that participants without diabetes who took the highest dose of tirzepatide lost an average of 22.5% of body weight over 72 weeks, more than triple what most pre-GLP-1 interventions achieved

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By the 1960s, researchers had demonstrated the incretin effect the phenomenon where glucose taken orally triggers much higher insulin release than glucose given intravenously