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What the research says Recent results from a late-stage clinical trial called REDEFINE 1, which included 3,417 people with overweight or obesity (without type 2 diabetes), showed that CagriSema led to almost 23% weight loss, surpassing cagrilintide and semaglutide alone

To manage gastrointestinal symptoms: Eat smaller, more frequent meals rather than large portions Avoid high-fat, fried, or heavily spiced foods Stay well hydrated, sipping water throughout the day Eat slowly and stop when comfortably satisfied Seek medical advice if you're unable to keep fluids down, as dehydration can lead to kidney problems

Additionally, be aware of potential side effects such as skin rashes , stomach pain , or even the premature graying of hair due to the reduction of melanin

SASP inflammatory signaling declines