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All oligos were resuspended in TE buffer at a concentration of 500 M

Upon activation by GLP-1RAs, GLP-1R initiates diverse intracellular cascades, such as the cyclic adenosine monophosphate (cAMP) / protein kinase A (PKA) pathway and phosphatidylinositol 3-kinase (PI3K) / protein kinase B (Akt) signaling pathway [1, 9]