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The autoimmunity can be to either be to thyroid peroxidase (TPO antibodies) or to thyroglobulin (TGB antibodies)

As evidence accrues, we, and others, will monitor what it means for the impact of GLP-1 medications on SMM, but so far we have not seen any compelling clinical data (although new systematic reviews and meta analyses have been proposed ) that GLP-1 medications lead to pathological skeletal muscle mass loss relative to what has been demonstrated and observed in other weight loss interventions

If you dont have a thyroid issue, you probably know someone who does

Methods and Study Design ARISTOTLE is a randomized, open-label, multicenter phase III trial conducted across 75 UK sites between October 2011 and July 2018