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Furthermore, mRNA vaccines contain adjuvants such as LNPs, which can trigger inflammatory cytokines, including interleukin (IL)-1 and IL-6, potentially contributing to ASIA (99, 100)
Attempts to increase exposure to UA have been made previously in the context of ischaemic stroke, one study finding that fewer patients underwent early ischaemic worsening after intravenous UA administration 54
doi: 10.1038/s41593-018-0120-6 41 ArajoSESMendonaHRWheelerNACampello-CostaPJacobsKMGomesFCAet al
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