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1 These agents act on GLP-1Rs in the periphery to increase insulin and inhibit glucagon secretion and in the brain to slow gastric emptying and suppress appetite, leading to weight loss

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Restarting the medication helped restore some protection, but only partially, showing that discontinuation leaves a lasting scar. What This Means for Patients For patients currently taking a GLP-1 medication, the key takeaway is this: If you are considering stopping, talk to your doctor first

With a simple, once-weekly GLP-1 treatment designed just for you, you could lose up to 20% of your body weight