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Tirzepatide is a dual GLP-1 / GIP receptor agonist medication that may be considered for certain patients as part of a physician-supervised weight-management plan

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Treatment assignment: emulation of randomization by propensity score-based overlap weighting To balance baseline characteristics between GLP-1RA initiators and noninitiators, we applied propensity score-based overlap weighting, which emphasizes the population with clinical equipoise 28

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