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Evidence comes from large-scale studies such as the SCALE and LEAD trials for liraglutide, the STEP 18 program for semaglutide, the SURMOUNT 14 trials for tirzepatide, AWARD-11 for dulaglutide, and DURATION-1 for exenatide (Table 3)
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Pregnant and Breastfeeding women Extensior 0.5 mg Injection is not recommended during pregnancy or breastfeeding
CJC-1295 with DAC has an approximately 8-day half-life allowing weekly or twice-weekly dosing, while CJC-1295 without DAC has a short half-life requiring frequent dosing matched to each Ipamorelin administration
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