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The two supplements that have the greatest level of evidence for melasma pigment & skin lightening include glutathione & polypodium extract

This treatment is generally safe for most healthy adults but is especially ideal for people dealing with: Post-acne pigmentation or dull skin Sun damage or melasma Fatigue or oxidative stress Frequent alcohol or toxin exposure (common in urban living) Those with certain medical conditions or allergies should consult with a medical provider beforehand

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Providers should assess patient tolerance and discontinue use if adverse reactions occur