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Respuesta Rpida: Los agonistas GLP-1 generalmente requieren uso continuo a largo plazo para mantener beneficios en diabetes tipo 2 y obesidad, aunque la duracin debe individualizarse segn respuesta clnica y tolerabilidad

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Nagahisa T, Kosugi S, Yamaguchi S (2023) Interactions between intestinal homeostasis and NAD(+) biology in regulating incretin production and postprandial glucose metabolism

The decline in mitochondrial function with age is a proposed mechanism for many neurodegenerative diseases, owing to the role of mito- chondria in preventing oxidative damage