Mr Mfazo Hove Featured in Newsweek: GLP-1 Medications and Vision Loss Posted Medically Reviewed by: Mr Mfazo Hove, Consultant Ophthalmic Surgeon Author: Chris Dunnington Published: July 16, 2026 Last Updated: July 16, 2026 Mr Mfazo Hove, Consultant Ophthalmic Surgeon and Medical Director of Blue Fin Vision, has been invited by Newsweek to comment on new international research linking GLP-1 medications to a rare optic nerve condition that can cause sudden vision loss
Despite binding to different receptors, their effects converge on protein kinases (PKA, PKB, PKC) and transcription factors like PPAR-gamma, a key regulator of lipid metabolism
Some individuals report that hunger feels more noticeable in the days immediately before their next scheduled dose sometimes described as 'wear-off' as plasma drug concentrations begin to decline
Acetaminophen Toxicity and 5-Oxoproline (Pyroglutamic Acid) A Tale of Two Cycles, One an ATP-Depleting Futile Cycle and the Other a Useful Cycle Michael Emmett Summary The acquired form of 5-oxoproline (pyroglutamic acid) metabolic acidosis was first described in 1989 and its relationship to chronic acetaminophen ingestion was proposed the next year
