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NK cell impairment is common in obesity, a disorder which is substantially rectified with SG by its apparent enhancement of the CD98-mTOR-glycolysis axis [84]
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With 17 DMTs available for the treatment of MS (Figure 1), clinicians are faced with the critical decision of how to screen MS patients for potential risk of malignancy with currently available DMTs and how to manage DMTs in MS patients who either had prior history of cancer or newly develop cancer while on a DMT
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