FIGURE 3 Discussion Unfortunately, the incidence of suicide is increasing and now represents the leading cause of mortality for people aged 15 to 44 years ( While the risk of death and suicide attempts is lower during and shortly after pregnancy than in the general female population, suicides account for up to 20% of all postpartum deaths and represent a leading cause of mortality in the peripartum period, which corroborates the high prevalence of suicide risk in our sample of women ( Under basal physiological conditions, there is a controlled balance between pro-oxidant molecules and antioxidant molecules, and an imbalance between these molecules is called oxidative stress ( Other studies examining blood serum and plasma GSH concentrations have also identified significantly lower GSH in MDD patients compared with healthy patients ( in vivo levels of GSH in the COC of unmedicated adults with MDD versus healthy controls ( Oxidative damage and redox dysregulation appear to play important roles in the pathogenesis of psychiatric disorders due to the brains vulnerability to the toxic effects of oxygen-free radicals ( Mechanisms of oxidative stress have been implicated in the pathogenesis of psychiatric disorders ( Conclusion Our work had some limitations, including the small sample size, the selection by the convenience of sample for the study, and the lack of follow-up of womens GSH levels at other time points (longitudinal study)
BPC-157 has a very short half-life and is typically cleared from the bloodstream within 24 to 36 hours
doi: 10.1186/s12935-018-0504-4 123 RovcaninBStojsavljevicAKekicDGopcevicKManojlovicDJovanovicMet al
However, the antioxidant benefits, reduction of oxidative stress, and improved natural killer cell function require that reduced glutathione is absorbed into the cells, not just in the plasma
