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In a phase II study, MariTide demonstrated weight loss of up to approximately 20% in people living with obesity without T2DM, compared with 2.6% in the placebo group and up to approximately 17% in those who have obesity and T2DM 10
The Notch1-Hes1 signaling pathway regulates cell differentiation, proliferation, and apoptosis
However, healthcare professionals may prescribe them off-label for weight loss
The researchers said this reduction in AFib risk remained consistent, regardless of the level of weight change
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