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Description

An intronic GAA repeat expansion in FGF14 causes the autosomal-dominant adult-onset ataxia SCA50/ATX-FGF14

In clinical trials studying Wegovy (2.4 mg), the average weight loss was 15%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone)

This action is thought to subsequently elevate levels of insulin-like growth factor-1 (IGF-1), which is viewed as the primary agent responsible for the anabolic action of growth hormone