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3 Interaction between NO and H 2 S in CRC The interplay between NO and hydrogen sulfide (H 2 S) constitutes a dynamic regulatory axis in CRC, with profound implications for redox balance, therapeutic resistance, and immune evasion

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In the uninfected state, upregulated genes were enriched in glycolysis/gluconeogenesis and the PI3K-Akt signaling pathway ( Figure 6B )indicating a Warburg-like metabolic state ideal for supplying energy and building blocks for viral replication ( Figure 5B )suggesting the cells protein synthesis machinery was pre-primed for high-throughput production

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