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Resultados adicionais in vitro descrevem alteraes na fosforilao de protenas de sinalizao de adeso focal envolvidas na ancoragem do citoesqueleto e na migrao celular

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(2014) reported a generally lower level of metabolites in PD as compared to controls, with a specific decrease in 3-hydroxyisovaleric acid, tryptophan, and creatinine, a significant decrease in the levels of A-38 and A-42, and an increase in soluble amyloid peptide precursor (APP) in CSF of patients