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Acknowledgements We appreciate the technical support from the Research Support Center, Graduate School of Medical Sciences, Kyushu University and partial support from intramural research funds of NIDDK, NIH

The human equivalent of roughly 0.035 mg represents a tiny fraction of the standard skin rejuvenation dose, suggesting that neurological benefits may occur alongside skin improvements at typical protocol dosages

Discussion The results of this systematic review illustrate the effects of diabetes mellitus (DM-I and DM-II) on reproductive parameters and fertility