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Low developmental competence and high tolerance to thermal stress of ovine oocytes in the warm compared with the cold season

The mtGSH maintains mitochondrial integrity and promotes adaptive survival responses induced by prolonged cytoplasmic GSH loss, including upregulation of anti-apoptotic proteins such as BCL2 37,38

Diets high in saturated fats and processed foods can lead to increased inflammation and oxidative stress, while diets rich in antioxidants like vitamins C and E, zinc, selenium, and omega-3 fatty acids help protect sperm from oxidative damage

Synaptic transmission is modulated by glucagon-like peptide 1 and glucose-dependent insulinotropic peptide mimetics GLP-1 and GIP receptor agonists are peptide hormones and growth factors, and share the neuroprotective effects of NGF and BDNF