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Whats really happening is a combination of metabolic stress, nutritional changes, endocrine shifts, and unmasking of pre-existing vulnerabilities

Keeping diet changes is less of a struggle, which increases the likelihood of long-term success

To direct the translation of the UGA codon into selenocysteine instead of a stop signal, it is needed a specialized tRNAs for its incorporation into proteins known as Selenocysteine Insertion Sequence (SECIS) [36]

GLP-1RA binding to GLP-1R is indeed mediated by internalization of GLP-1R and GLP-1RA, consistent with the fact that GLP-1R is classified as a class B G protein-coupled receptor (GPCR) [57,58]