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It can allow for more gradual escalation of doses when starting treatment and reduce the GI side effects that most commonly occur during this period, says Kushner

Open Forum Infectious Diseases, 12 (Supplement 1)

11,12 Very recently, a small cohort study ( n = 28) reported a higher incidence of thyroid dysfunction in patients treated with ipilimumab and nivolumab combination therapy who had widespread hypoechogenicity in the thyroid (5/9 patients) than in those without hypoechogenicity (2/18 patients)

Under the partnership, the two companies plan to gradually expand collaboration on efpeglenatide and other metabolic disease treatments