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SCD1 catalyzes the synthesis of monounsaturated fatty acids (MUFAs), thereby reducing the proportion of oxidizable polyunsaturated fatty acids (PUFAs) in membrane lipids and decreasing cellular sensitivity to ferroptosis ( In vitro , the USP7 inhibitor DHPO significantly reduced the proliferative activity of GC cells and induced lipid peroxidation and iron accumulation, exhibiting hallmark features of ferroptosis

Regular monitoring and follow-up injections can help maintain optimal Vitamin B12 levels and prevent deficiency-related health issues