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Health Benefits of Folate To date, folate has been found to show positive effects in cardiovascular, hematopoiesis, neurological, and neural tube protection, as well as in anti-cancer, gut homeostasis, and immune response, which will be discussed in detail below (Figure 3)

MPC1-deficient C2C12 cells were generated by CRISPR and cultured as described (Oonthonpan, Rauckhorst, Gray, Boutron, & Taylor, 2019)