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however, the potential for weight loss with the GLP-1 incretin mimetics can be a motivator for some patients

In this context, collected data are presented to manifest that sulfonylureas are capable of impacting other ion channels besides K ATP channels, such as TRP and BK Ca , via direct and indirect ways, exhibiting the involvement of diverse ion channels in the modulation of insulin secretion and antidiabetic actions (see Table 1)

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Liraglutide reduces the body weight and waist circumference in Chinese overweight and obese type 2 diabetic patients