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TB-500 thus exhibits similar behavior and outcomes to TB4 in clinical studies

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Researchers are calling for larger, well-designed randomized controlled trials in humans to determine whether these impressive animal results translate to clinical practice

Our findings are in agreement with other recent observations using similar ligature models, which show a considerable increase of the distance between the cemento-enamel junction and the alveolar crest, regarded as a sign of alveolar bone loss (48, 52)